The project is focused on scientific issues such as the regional cycling and evolution of toxic organic pollutants on the background of high intensity human activities, and the mechanism for interactions between natural media and toxic organic pollutants. Research was carried out at two levels, i.e., macroscopic and microscopic, and in five aspects, i.e., pollution history and evolution of toxic organic pollutants in the Pearl River Delta environment, high risk areas in terms of deposition of toxic organic pollutants, atmospheric distribution and origin of such pollutants, geological absorbents and absorption-desorption dynamics, environmental minerals, nanometer materials and radiation reaction dynamics, and innovative research results were made in the five aspects. By means of deposition records, the regional pollution history of persistent organic pollutants (POPs) was recovered and their relationship with economic development in this area was explored. Two high risk areas of POPs were delineated for the first time, and the mechanism for their formation and evolution were discussed. Also the absorption and desorption dynamics of geological absorbents and POPs were studied in depth and for the first time, a carbon isotope analytical method for atmospheric carboxyl compounds was set up.